Engineering Manager - Agentic AI

🏢 Heartflowinc · 📍 San Francisco, California 💰 $200,000 - $270,000 / yr

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Position Summary & Responsibilities

Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause of death worldwide, using cutting-edge technology. The flagship product—an AI-driven, non-invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFR_CTAnalysis—provides a color-coded, 3D model of a patient’s coronary arteries indicating the impact blockages have on blood flow to the heart. Heartflow is the first AI-driven non-invasive integrated heart care solution across the CCTA pathway that helps clinicians identify stenoses in the coronary arteries (RoadMap™Analysis), assess coronary blood flow (FFR_CTAnalysis), and characterize and quantify coronary atherosclerosis (Plaque Analysis). Our pipeline of products is growing and so is our team; join us in helping to revolutionize precision heartcare.

Heartflow is a publicly traded company (HTFL) that has received international recognition for exceptional strides in healthcare innovation, is supported by medical societies around the world, cleared for use in the US, UK, Europe, Japan and Canada, and has been used for more than 750,000 patients worldwide.

About the role

To accelerate this mission, we are seeking an Engineering Manager to build and lead our new Agentic AI initiatives team.

This is a unique "player-coach" opportunity. You will start in a deeply hands-on capacity - acting as the lead architect and foundational engineer to set up the core ecosystem that allows autonomous, intelligent agents to execute multi-step medical reasoning securely and at scale. As the foundation is laid and the product gains momentum, your role will transition into a full Engineering Manager capacity. You will be responsible for scaling a world-class team of engineers, guiding their execution, and shaping the long-term technical strategy of the platform.

You will have a true blank-canvas opportunity to design production-grade agentic systems from scratch, directly translating our decade-plus of clinical AI success into the next generation of autonomous medical technology.

Job Responsibilities

Initial Hands-On Execution: Design, architect, and write code for a robust, secure, and scalable Agentic AI platform, establishing standard patterns for multi-agent orch

🎯 Candidate Preparation Guide For Heartflowinc Applicants

Key Role Competencies & Evaluation Highlights

Key Role Focus:

The medical technology panel strictly evaluates clinical precision, regulatory (FDA) clearance awareness, and the ability to translate advanced computational fluid dynamics into cardiology insights.

📋 Preparation Priorities (Key Areas to Clarify):

1. Minimizes the strict regulatory validation steps required for software-as-a-medical-device (SaMD)
2. Shows casual regard for data accuracy in life-critical diagnostic software
3. Lacks the technical depth to discuss numerical simulation or clinical workflow integration

✨ Recommended Role Alignment Hook:

I scale life-saving medical software by pairing rigorous regulatory compliance with cutting-edge computational cardiovascular insights.

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