Senior Software Engineer

🏢 Karius · 📍 Redwood City, CA (Hybrid) · 💼 hybrid · ⏰ Full-time 💰 $128,960 - $193,440 / yr

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Position Summary & Responsibilities

About Karius

Karius is a life science, venture-backed clinical metagenomics company, focused on elevating patient care through microbial insights. We are committed to advancing diagnostic science and technology to optimize the diagnosis and treatment of infectious diseases. Through the use of genomics and AI, we are driven to improve the diagnostic landscape for infectious diseases. Karius delivers unprecedented diagnostic insight detecting microbial cell-free DNA circulating in the body to assist physicians to make rapid treatment decisions.

Position Summary

We are building and operating a unique software stack of cloud infrastructure, software services, APIs, web and mobile interactive interfaces, and AI-driven data analytics pipelines to deliver life-saving results in the highly complex infectious disease landscape. We believe the success of Karius’ products is driven by both our unique technology and the elegance of the software solution.The Senior Software Engineer will play a key role in designing, developing, and maintaining scalable, reliable software solutions that support Karius’ products and mission. This role requires strong technical judgment, thoughtful problem-solving, and close collaboration across engineering, product, scientific, and clinical teams.

Why Should You Join Us?

🎯 Candidate Preparation Guide For Karius Applicants

Key Role Competencies & Evaluation Highlights

Key Role Focus:

Genomic data interpretation rigor, clinical laboratory standards compliance (CLIA/CAP), and passion for translating metagenomic sequencing into life-saving diagnostics.

📋 Preparation Priorities (Key Areas to Clarify):

1. Treating patient data or assay quality control with casual indifference or sloppy documentation
2. Inability to communicate complex genomic data clearly to clinicians and non-technical stakeholders
3. Lack of rigor in handling false positives/negatives in diagnostic development

✨ Recommended Role Alignment Hook:

I leverage advanced genomics and microbial cell-free DNA to dramatically accelerate the diagnosis of infectious diseases.

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