(Contract) Research Technician, Pre-clinical Pharmacology

🏢 Manifoldbio · 📍 Boston · 💼 onsite 💰 $60,000 - $70,000 / yr

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Position Summary & Responsibilities

Contract length: 12 months

Compensation: $30-$35/hour

Hours: 40 hours/week

Location: On-site 5 days/week in Boston (Fenway Area)

Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems. Using proprietary molecular barcoding technology, we screen hundreds of thousands of protein designs simultaneously in living systems, producing in vivo-validated datasets at a scale no one else can match. The datasets power our computational models, which leads to better drug designs, creating a flywheel that gets stronger with every campaign. Our team of protein engineers, biologists, and computational scientists works across this full stack to pursue programs both internally and with leading pharma companies.

Position

Manifold Bio is looking for an organized, motivated In-Vivo Research Technician to join our pharmacology team on a one-year contract. You will work alongside experienced researchers to prepare for and execute mouse studies supporting our internal drug discovery programs. This role is deliberately structured around training and growth. We are looking for someone with excellent organizational instincts, and genuine enthusiasm for learning the rest. Dosing routes, blood collection, necropsy and tissue processing can all be taught, and we are committed to teaching them. For the right person, this contract is intended as a path toward a permanent Research Associate position.

Required Qualifications

Prepare and label tubes, cages and collection supplies ahead of each study
Set up procedure rooms for dosing days and takedowns
Hands-on experience with animal handling, including the ability to confidently scruff a mouse
Comfort working with laboratory animals in a vivarium environment
Tattoo and tail-mark mice; prepare and organize study cages
Weigh animals and record data accurately
Maintain study records in Benchling
Help maintain lab and vivarium inventories
Support necropsy and tissue collection (training provided)
Process collected samples, pr

🎯 Candidate Preparation Guide For Manifoldbio Applicants

Key Role Competencies & Evaluation Highlights

Key Role Focus:

Scientific rigor combined with high-velocity engineering is tested intensely; interviewers look for pioneers who can build multiplexed protein measurement platforms at scale.

📋 Preparation Priorities (Key Areas to Clarify):

1. Working strictly in academic silos without an appreciation for commercial drug discovery timelines
2. Inability to troubleshoot unexpected assay failures with data-driven pragmatism
3. Resistance to cross-disciplinary collaboration between wet-lab scientists and computational teams

✨ Recommended Role Alignment Hook:

I build high-throughput protein measurement engines that accelerate therapeutic discovery by turning complex biological data into actionable insights.

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