Bio-Analytical Co-op-Northeastern Students

🏢 Seaporttherapeutics · 📍 Boston, MA

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Position Summary & Responsibilities

Seaport Therapeutics is a clinical-stage therapeutics company advancing the development of novel neuropsychiatric medicines in areas of high unmet patient needs. The Company has a proven strategy of advancing clinically validated mechanisms previously held back by limitations that are overcome with its proprietary GlyphTM technology platform. All the therapeutic candidates in its pipeline of first and best-in-class medicines are based on the Glyph platform, which is uniquely designed to enable oral bioavailability, bypass first-pass metabolism and reduce hepatotoxicity and other side effects. Seaport is led by an experienced team that invented and advanced important neuropsychiatric medicines and are guided by an extensive network of renowned scientists, clinicians and key opinion leaders. For more information, please visit www.seaporttx.com.

Job Description

Seaport Therapeutics is seeking a co-op student for a lab-based bioanalysis position to be part of our Discovery team. This co-op will have a focus on LC-MS to assist in the screening of novel drugs. We are looking for a highly motivated individual who is looking to be a part of a multidisciplinary team and to gain experience in a startup environment. This position will contribute to advancing the pipeline of impactful candidates generated from our novel Glyph™ prodrug platform.

Some of the responsibilities will include:

Executing in vitro experiments, using LC-MS, for the screening of lipid prodrugs to support preclinical discovery
Processing and analyzing in vivo samples (plasma, lymph fluid, etc.) to generate DMPK data for various prodrugs

Contributing to the development and optimization of LC-MS methods for both quantitative and qualitative analysis
Routine use and troubleshooting of LC-MS instrumentation
Documenting all experiments using an electronic notebook and analyzing data for reports and regular internal presentations

Experience and Skills

Enrolled in a Chemistry, Biochemistry, Pharmaceutical Sciences, Chemical Engineering, or related program at the Master’s Level
Previous Co-op or lab experience is preferred
Knowledge of or experience with: HPLC, reverse phase chromatography, mass spectrometry instrumentation, enzym

🎯 Candidate Preparation Guide For Seaporttherapeutics Applicants

Key Role Competencies & Evaluation Highlights

Key Role Focus:

Rigorous scientific and strategic scrutiny focused on translational research capability, neurobiology expertise, and clinical pipeline acceleration.

📋 Preparation Priorities (Key Areas to Clarify):

1. Superficial grasp of CNS mechanisms or proprietary platform technologies.
2. Inability to defend experimental design choices against critical scientific inquiry.
3. Siloed mindset that disregards regulatory or commercial realities.

✨ Recommended Role Alignment Hook:

I accelerate CNS drug discovery pipelines by pairing rigorous neurobiology expertise with translational execution strategies.

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