Executive Director/Vice President, Clinical Development

🏢 Seaporttherapeutics · 📍 Boston, MA 💰 $297,000 - $340,000 / yr
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Position Summary & Responsibilities

 

Seaport Therapeutics is a clinical-stage therapeutics company advancing the development of novel neuropsychiatric medicines in areas of high unmet patient needs. The Company has a proven strategy of advancing clinically validated mechanisms previously held back by limitations that are overcome with its proprietary GlyphTM technology platform. All the therapeutic candidates in its pipeline of first and best-in-class medicines are based on the Glyph platform, which is uniquely designed to enable oral bioavailability, bypass first-pass metabolism and reduce hepatotoxicity and other side effects. Seaport is led by an experienced team that invented and advanced important neuropsychiatric medicines and are guided by an extensive network of renowned scientists, clinicians and key opinion leaders. For more information, please visit www.seaporttx.com.

Seaport Therapeutics is seeking a hands-on clinical development leader to drive the strategic and operational execution of our global clinical programs across current and future pipeline assets. This role will report to the Chief Medical Officer and oversee clinical trial design and execution, partner with regulatory strategy, biostatistics, program management and other cross-functional stakeholders and external partners including regulatory agencies, KOLs, and investigators. The ideal candidate will bring deep expertise in neuroscience or neurology, a proven track record of successful IND/NDA submissions, experience with Ph III clinical development, and a passion for partnering with high-performing teams and advancing innovative therapies in neurological and neuropsychiatric diseases.

 

The ideal candidate will embrace a collaborative, innovative culture that embodies our values of service to patients impacted by mental health conditions, with a “we own it” mentality, demonstrating entrepreneurial spirit and technical excellence while fostering teamwork and continuous improvement. This position is based in Boston’s Seaport area, with a strong preference for being onsite 4 days per week.

Primary Responsibilities

· Establish and drive the clinical development strategy and hands-on tactical execution plans on programs against the current and future development portfolio.

· Manage effective internal and external relationships, internally with members of the executive leadership team, regulatory affairs, clinical operations and medical affair

🎯 Candidate Preparation Guide For Seaporttherapeutics Applicants

Key Role Competencies & Evaluation Highlights

Key Role Focus:

Rigorous scientific and strategic scrutiny focused on translational research capability, neurobiology expertise, and clinical pipeline acceleration.

📋 Preparation Priorities (Key Areas to Clarify):
  • 1. Superficial grasp of CNS mechanisms or proprietary platform technologies.
  • 2. Inability to defend experimental design choices against critical scientific inquiry.
  • 3. Siloed mindset that disregards regulatory or commercial realities.
✨ Recommended Role Alignment Hook:

I accelerate CNS drug discovery pipelines by pairing rigorous neurobiology expertise with translational execution strategies.

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